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Their data suggest that NF-κB inhibitors can mitigate cellular damage and could provide clinical benefit for degenerative changes caused by aging.
Preventing cellular aging and aging-related degenerative diseases

(Journal of Clinical Investigation) Age-associated degeneration is caused, at least in part, by accumulated cellular damage, including DNA damage, but how these types of damage drive aging remains unclear. Dr. Paul Robbins and colleagues at the University of Pittsburgh sought to address this question.