Oncolytic viruses effectively target and kill pancreatic cancer stem cells - EurekAlert (article link)
- Parent Category: News
21 May 2011
- Published: 21 May 2011
(Digestive Disease Week) Oncolytic viruses quickly infect and kill cancer stem cells, which may provide a treatment for tumors that are resistant to conventional chemotherapy and radiation, particularly pancreatic cancer, according to new research from Memorial Sloan-Kettering Cancer Center in New York. The findings are especially important since pancreatic cancer has a poor prognosis and is difficult to detect and treat at early stages.
"Investigators sought to determine whether the viruses containing a marker gene that expresses green fluorescent protein could infect pancreatic cancer stem cells and ultimately kill the cancer stem cell. Their findings were promising and documented that viral activity was correlated with green fluorescent protein expression."